1,1,3,3-四甲氧基丙烷合成路线 （共 127 条）
反应条件
(i) N-methylpiperidine, (ii) HCl; Multistep reaction;
参考文献
Pharmaceutical Chemistry Journal, , vol. 7, # 9 p. 545 - 549
Khimiko-Farmatsevticheskii Zhurnal, , vol. 7, # 9 p. 6 - 11
参考文献
Bulletin de la Societe Chimique de France, , p. 1129 - 1135
反应条件
hydrogenchloride; ozone 1.) -40 deg C, 2.) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Monatshefte fuer Chemie, , vol. 121, p. 203 - 207
参考文献
Zhurnal Obshchei Khimii, , vol. 27, p. 57,58,61;engl.Ausg.S.65,67,68
反应条件
1: With trimethylsilyl trifluoromethanesulfonate in dichloromethane T=-78 - 20°C; 2: With hydrogenchloride in dichloromethane Further stages.;
参考文献
Sher, Muhammad; Tam Dang; Ahmed, Zafar; Rashid, Muhammad A.; Fischer, Christine; Langer, Peter
Journal of Organic Chemistry, 2007 , vol. 72, # 16 p. 6284 - 6286
反应条件
titanium tetrachloride in dichloromethane T=-78 - 20°C; 14 h;
参考文献
Mross, Gerson; Langer, Peter
Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8519 - 8521
反应条件
in ethanol 1 h; Heating;
参考文献
De La Hoz, Antonio; Diaz-Ortiz, Angel; Elguero, Jose; Martinez, Luis J.; Moreno, Andres; Sanchez-Migallon, Ana
Tetrahedron, 2001 , vol. 57, # 20 p. 4397 - 4403
反应条件
acetic acid 2 h; Heating;
参考文献
Troschutz; Dennstedt
Archiv der Pharmazie, 1994 , vol. 327, # 2 p. 85 - 89
反应条件
in ethanol 1 h; Reflux;
参考文献
Velcicky, Juraj; Feifel, Roland; Hawtin, Stuart; Heng, Richard; Huppertz, Christine; Koch, Guido; Kroemer, Markus; Moebitz, Henrik; Revesz, Laszlo; Scheufler, Clemens; Schlapbach, Achim
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 1293 - 1297
