N-氰亚胺基-S,S-二硫代碳酸二甲酯合成路线 （共 58 条）
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide
T=20°C; 18 h;
2: With piperidine in N,N-dimethyl-formamide
T=60°C; 12 h;
参考文献
Teague, Simon J.
Journal of Organic Chemistry, 2008 , vol. 73, # 24 p. 9765 - 9766
参考文献
Abbott Laboratories
Patent: US6645968 B2, 2003 ;
US 6645968 B2
参考文献
Tominaga; Ogata; Kohra; Hojo; Hosomi
Tetrahedron Letters, 1991 , vol. 32, # 42 p. 5987 - 5990
反应条件
in methanol
T=20°C; 1 h;
参考文献
Reiter, J.; Somorai, T.; Jerkovich, Gy.; Dvortsak, P.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1157 - 1164
反应条件
pyridine in ethanol
9 h; Heating;
参考文献
Szilagyi, Geza; Somorai, Tamas; Bozo, Eva; Lango, Jozsef; Nagy, Gabor; et al.
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 2 p. 95 - 101
反应条件
in isopropyl alcohol
4 h; Heating;
参考文献
Reiter, J.; Somorai, T.; Jerkovich, Gy.; Dvortsak, P.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1157 - 1164
反应条件
1: dimethyl N-cyano-dithioimidocarbonate With sodium sulfide in N,N-dimethyl-formamide
T=70°C; 2 h;
2: chloroacetonitrile in N,N-dimethyl-formamide
T=70°C; 2 h;
3: With potassium carbonate in N,N-dimethyl-formamide
T=70°C; 1 h; Further stages.;
参考文献
Thomae, David; Perspicace, Enrico; Hesse, Stephanie; Kirsch, Gilbert; Seck, Pierre
Tetrahedron, 2008 , vol. 64, # 39 p. 9309 - 9314
反应条件
sodium hydroxide; hydroxylamine hydrochloride
参考文献
Wittenbrook,L.S.
Journal of Heterocyclic Chemistry, 1975 , vol. 12, p. 37 - 42
