N1-(2,4-二甲氧基苯基)-2-氯乙胺合成路线 (共 9 条)
反应条件
in N,N-dimethyl-formamide T=20°C; 3 h; Inert atmosphere;
参考文献
Gawande, Shrikant S.; Warangkar, Suchita C.; Bandgar, Babasaheb P.; Khobragade, Chandrahasya N.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 10 p. 2772 - 2777
反应条件
2: hydrogen sulfide; aqueous ammonia 3: acetic acid 4: alkaline solution 5: diluted hydrochloric acid 6: acetic acid; sodium acetate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 41, p. 1457
反应条件
1: diluted hydrochloric acid 2: acetic acid; sodium acetate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 41, p. 1457
反应条件
1: hydrogen sulfide; aqueous ammonia 2: acetic acid 3: alkaline solution 4: diluted hydrochloric acid 5: acetic acid; sodium acetate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 41, p. 1457
反应条件
1: acetic acid 2: alkaline solution 3: diluted hydrochloric acid 4: acetic acid; sodium acetate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 41, p. 1457
反应条件
1: alkaline solution 2: diluted hydrochloric acid 3: acetic acid; sodium acetate View Scheme
参考文献
Journal of the American Chemical Society, , vol. 41, p. 1457
反应条件
1: 76 percent / AlCl3 / CH2Cl2 / 16 h / Ambient temperature 2: 78 percent / K2CO3 / acetone / 5 h / Heating View Scheme
参考文献
Booher; Kornfeld; Smalstig; Clemens
Journal of Medicinal Chemistry, 1987 , vol. 30, # 3 p. 580 - 583
反应条件
1: 76 percent / AlCl3 / CH2Cl2 / 16 h / Ambient temperature 2: 78 percent / K2CO3 / acetone / 5 h / Heating 3: K2CO3 / acetone / 72 h / Heating View Scheme
参考文献
Booher; Kornfeld; Smalstig; Clemens
Journal of Medicinal Chemistry, 1987 , vol. 30, # 3 p. 580 - 583
反应条件
1: AlCl3; NaCl / 140 °C
2: aqueous NaOH
View Scheme
参考文献
Loudon; Ogg
Journal of the Chemical Society, 1955 , p. 739,743