2-氨基-5-甲氧基吡啶合成路线 （共 19 条）
反应条件
hydrazine; palladium 10 on activated carbon in ethanol 0.75 h; Heating / reflux;
参考文献
BIOLIPOX AB
Patent: WO2007/51982 A1, 2007 ;
Location in patent: Page/Page column 49 ;
反应条件
hydroxylamine hydrochloride; triethylamine in ethanol; water 20 h; Heating / reflux;
参考文献
Tibotec Pharmaceuticals Ltd.
Patent: WO2007/113290 A1, 2007 ;
Location in patent: Page/Page column 40-42 ;
反应条件
copper in methanol T=100°C; 12 h;
参考文献
Van De Poel, Herve; Guillaumet, Gerald; Viaud-Massuard, Marie-Claude
Heterocycles, 2002 , vol. 57, # 1 p. 55 - 71
反应条件
copper in methanol T=160°C;
参考文献
MYRIAD GENETICS, INC.; CYTOVIA, INC.
Patent: WO2005/3100 A2, 2005 ;
Location in patent: Page 231 ;
WO 2005/003100 A2
反应条件
hydrazine hydrate; palladium monocarbide in ethanol; water
反应条件
1: 80 percent / conc. H2SO4; fum. HNO3 / 4 h / 50 °C 2: 95 percent / N2H4*H2O / 5 percent Pd/C / ethanol / 1.5 h / Heating View Scheme
参考文献
Pharmazie, , vol. 55, # 12 p. 907 - 912
反应条件
sodium methylate in methanol
反应条件
copper acetylacetonate; potassium phosphate; ammonia in N,N-dimethyl-formamide T=90°C; 24 h; GloveboxAutoclave; chemoselective reaction;
参考文献
Fantasia, Serena; Windisch, Johannes; Scalone, Michelangelo
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 627 - 631
反应条件
sodium; copper T=160°C; 48 h;
参考文献
Trapani, Giuseppe; Franco, Massimo; Ricciardi, Laura; Latrofa, Andrea; Genchi, Giuseppe; Sanna, Enrico; Tuveri, Francesca; Cagetti, Elisabetta; Biggio, Giovanni; Liso, Gaetano
Journal of Medicinal Chemistry, 1997 , vol. 40, # 19 p. 3109 - 3118
反应条件
1: 96 percent / copper(I) chloride / methanol; dimethylformamide / 2 h / 80 °C 2: 81 percent / hydroxylamine hydrochloride; triethylamine / ethanol; H2O / 20 h / Heating View Scheme
参考文献
European Journal of Organic Chemistry, , # 20 p. 3948 - 3957
