4,5-二甲氧基-2-硝基苯甲醇合成路线 （共 10 条）
反应条件
sodium tetrahydroborate in ethanol
参考文献
Reinhard, Robert; Schmidt, Brigitte F.
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2434 - 2441
反应条件
(RS)-1-(3,5-dimethoxyphenyl)-2-oxo-2-phenylethyl 4-aminobutanoate hydrochloride IrradiationPhotolysis;
参考文献
Chemical Communications, , vol. 48, # 5 p. 657 - 659
反应条件
pH=7.4; Photolysisaq. phosphate bufferUV-irradiation;
参考文献
Macromolecules, , vol. 44, # 21 p. 8590 - 8597
反应条件
in tetrahydrofuran; toluene T=0°C; 4 h;
参考文献
Lehmann, Juerg; Linden, Anthony; Heimgartner, Heinz
Helvetica Chimica Acta, 1999 , vol. 82, # 6 p. 888 - 908
反应条件
pyridine in dichloromethane Acylation; 0.166667 h;
参考文献
Kearney, Patrick C.; Nowak, Mark W.; Zhong, Wenge; Silverman, Scott K.; Lester, Henry A.; Dougherty, Dennis A.
Molecular Pharmacology, 1996 , vol. 50, # 5 p. 1401 - 1412
反应条件
pyridine; phosphorus tribromide in benzene 24 h;
参考文献
Wilcox, Mary; Viola, Randall W.; Johnson, Katherine W.; Billington, Andrew P.; Carpenter, Barry K.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1585 - 1589
反应条件
thionyl chloride in dichloromethane Substitution; 3 h;
参考文献
Kearney, Patrick C.; Nowak, Mark W.; Zhong, Wenge; Silverman, Scott K.; Lester, Henry A.; Dougherty, Dennis A.
Molecular Pharmacology, 1996 , vol. 50, # 5 p. 1401 - 1412
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane Inert atmosphere;
参考文献
Fomina, Nadezda; McFearin, Cathryn; Sermsakdi, Marleen; Edigin, Osayimwense; Almutairi, Adah
Journal of the American Chemical Society, 2010 , vol. 132, # 28 p. 9540 - 9542
反应条件
macroporous polystyrene-supported IBX amide in acetonitrile T=20°C; 4 h;
参考文献
Jang, Hyung-Seok; Chung, Woo-Jae; Lee, Yoon-Sik
Tetrahedron Letters, 2007 , vol. 48, # 21 p. 3731 - 3734
反应条件
1: 85 percent / K2CO3; Et3N / CH2Cl2 / 24 h / 20 °C
2: CF3SO3H / CH2Cl2 / 20 °C
3: Pd(Ph3P)4; N-methylmorpholine; acetic acid / CHCl3 / 4 h / 20 °C
View Scheme
参考文献
Veldhuyzen, Willem F.; Nguyen, Quan; McMaster, Gary; Lawrence, David S.
Journal of the American Chemical Society, 2003 , vol. 125, # 44 p. 13358 - 13359
