methyllithium

lithium diisopropyl amide in diethyl ether T=-20°C; 5 h; Yield given;

Dowex 50 Wx4 in diethyl ether; water T=-78 - 20°C; Rearrangement;

Dowex 50 Wx4 in diethyl ether; water T=-78 - 20°C; Rearrangement;

1: 1-bromobicyclolt;1.1.0gt;butane With tert.-butyl lithium in diethyl ether T=0°C; Metallation; lithium/bromine exchange; 2 h; 2: With tributyltin chloride T=20°C; transmetalation; 2 h; 3: para-iodoanisole With tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=65°C; Stille cross-coupling; 24 h;