2-烯丙基-2-(2-丙炔基)丙二酸二乙酯合成路线 （共 29 条）
反应条件
lithium diisopropyl amide in tetrahydrofuran; hexane; toluene T=-78°C; 1 h;
参考文献
Yeo, Sung Jin; Jeong, Kyung Seok; Han, Hogyu; Kim, Jaheon; Jeong, Nakcheol
Tetrahedron Letters, 2006 , vol. 47, # 41 p. 7389 - 7393
反应条件
1: (2-propynyl)propanedioic acid diethyl ester With sodium hydride in tetrahydrofuran T=0 - 20°C; Inert atmosphere; 2: allyl bromide in tetrahydrofuran T=20°C; 3 h; Inert atmosphere;
参考文献
Benedetti, Erica; Simonneau, Antoine; Hours, Alexandra; Amouri, Hani; Penoni, Andrea; Palmisano, Giovanni; Malacria, Max; Goddard, Jean-Philippe; Fensterbank, Louis
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1908 - 1912
反应条件
1: (2-propynyl)propanedioic acid diethyl ester With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.5 h; Inert atmosphere; 2: propargyl bromide T=0 - 20°C; 20.5 h; Inert atmosphere;
参考文献
Trost, Barry M.; Breder, Alexander; Okeefe, B. Michael; Rao, Meera; Franz, Adam W.
Journal of the American Chemical Society, 2011 , vol. 133, # 13 p. 4766 - 4769
反应条件
1.1: potassium carbonate / dimethyl sulfoxide / 0.5 h / 0 °C 1.2: 7 h / 0 - 20 °C 2.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 0 °C 2.2: 15 h / 0 - 20 °C View Scheme
参考文献
Asano, Keisuke; Uesugi, Yuki; Yoshida, Jun-Ichi
Organic Letters, 2013 , vol. 15, # 10 p. 2398 - 2401
参考文献
Schulte et al.
Archiv der Pharmazie (Weinheim, Germany), 1958 , vol. 291, p. 227,236
参考文献
Chatani, Naoto; Takeyasu, Takumi; Horiuchi, Nobuhiko; Hanafusa, Terukiyo
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3539 - 3548
反应条件
triethylsilane; indium(III) chloride; triethyl borane in hexane; acetonitrile T=0°C; 2 h;
参考文献
Organic Letters, , vol. 6, # 26 p. 4981 - 4983
反应条件
[Co3(μ3-CH)-(CO)7(PMe2Ph)2] in toluene T=120°C; intermolecular Pauson-Khand reaction; P=7500.75 Torr; 10 h; Product distribution; Further Variations:Catalysts;
参考文献
Dalton Transactions, , # 18 p. 2442 - 2453
反应条件
(IPr2,6-(2,6-iPr2C6H3N=CMe)2C5H3N)Fe(N2)2; hydrogen in benzene T=23°C; P=3040.2 Torr; 3 h; Inert atmosphere; optical yield given as percent de;
参考文献
Sylvester, Kevin T.; Chirik, Paul J.
Journal of the American Chemical Society, 2009 , vol. 131, # 25 p. 8772 - 8774
反应条件
water; triethylamine; PS-PEG resin supported bisphosphine-palladium complex Sonogashira coupling; 1.5 h; Heating;
参考文献
Nakai, Yasushi; Kimura, Tsutomu; Uozumi, Yasuhiro
Synlett, 2006 , # 18 p. 3065 - 3068
