二乙基(2-氰乙基)膦酸酯合成路线 （共 3 条）
参考文献
Arbuzov,B.A. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1972 , vol. 21, p. 1103 - 1105
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1972 , vol. 21, p. 1153 - 1155
反应条件
phosphoric acid; phosphorus trichoride
参考文献
Bandurina,T.A. et al.
Pharmaceutical Chemistry Journal, 1978 , vol. 12, p. 1428 - 1431
Khimiko-Farmatsevticheskii Zhurnal, 1978 , vol. 12, # 11 p. 35 - 37
反应条件
1: With sodium tetrahydroborate; cobalt(II) chloride in methanol
T=-30 - 20°C;
2: With hydrogenchloride in water
3: With ammonia in water
pH=9;
参考文献
UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Patent: WO2005/115150 A2, 2005 ;
Location in patent: Page/Page column 89 ;
WO 2005/115150 A2
