2-甲氧基-4-硝基苯甲腈合成路线 （共 21 条）
反应条件
Pd(PPh3)4 in N,N-dimethyl-formamide; toluene
参考文献
Bristol-Myers Squibb Company
Patent: US6596747 B2, 2003 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide 2 h;
参考文献
Mackman; Katz; Breitenbucher; Hui; Verner; Luong; Liu; Sprengeler
Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3856 - 3871
反应条件
in N,N-dimethyl-formamide; toluene
参考文献
Bristol-Myers Squibb Co.
Patent: US6399773 B1, 2002 ;
反应条件
1-methyl-piperidine; toluene
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2226,2235
反应条件
1: 31 percent / hexamethylphosphoric acid triamide / 0.5 h / 150 °C 2: 89 percent / K2CO3 / dimethylformamide / 2 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 44, # 23 p. 3856 - 3871
反应条件
2: triethylamine; toluene View Scheme
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2226,2235
反应条件
potassium carbonate; m-xylene
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2226,2235
反应条件
potassium carbonate; m-xylene
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2226,2235
参考文献
Imakura; Okimoto; Konishi; Hisazumi; Yamazaki; Kobayashi; Yamashita
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 7 p. 1691 - 1696
反应条件
hydrogenchloride; water; copper(II) sulfate
参考文献
Journal of the Chemical Society, , p. 861,864
