6-氯-2-甲基吡嗪-3(2H)-酮合成路线 （共 3 条）
反应条件
potassium carbonate; tetrabutylammomium bromide in acetonitrile T=115°C; 5 h;
参考文献
PIERRE FABRE MEDICAMENT; DUPONT-PASSELAIGUE, Elisabeth; MIALHE, Samuel; RIEU, Jean-Pierre; JUNQUERO, Didier; VALEILLE, Karine
Patent: WO2011/15629 A1, 2011 ;
Location in patent: Page/Page column 68; 69 ;
WO 2011/015629 A1
参考文献
Eichenberger et al.
Helvetica Chimica Acta, 1954 , vol. 37, p. 837,848
反应条件
caesium carbonate; PhCH2Pd(PPh3)2Cl in ethylene glycol dimethyl ether; ethanol; water
T=150°C; 0.166667 h;
参考文献
ASTRAZENECA AB
Patent: WO2007/8144 A1, 2007 ;
Location in patent: Page/Page column 17 ;
WO 2007/008144 A1
