3-溴-4-氟苯甲酸合成路线

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AMGEN INC.
Patent: WO2007/61930 A1, 2007 ;
Location in patent: Page/Page column 63 ;
WO 2007/061930 A1

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BEAULIEU, Pierre; BONNEAU, Pierre; COULOMBE, Rene; FORGIONE, Pasquale; GILLARD, James; JAKALIAN, Araz; RANCOURT, Jean
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WO 2010/037210 A1

1007-16-53-溴-4-氟苯甲酸

929884-90-2

参考文献

Chawla, Gita; Kumar, Umesh; Bawa, Sandhya; Kumar, Jagdish
Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 5 p. 658 - 665,8

1007-16-53-溴-4-氟苯甲酸+

765-30-0环丙胺

639858-63-2N-环丙基-3-溴-4-氟苯甲酰胺

参考文献

Borzilleri, Robert M.; Bhide, Rajeev S.; Barrish, Joel C.; D'Arienzo, Celia J.; Derbin, George M.; Fargnoli, Joseph; Hunt, John T.; Jeyaseelan Sr., Robert; Kamath, Amrita; Kukral, Daniel W.; Marathe, Punit; Mortillo, Steve; Qian, Ligang; Tokarski, John S.; Wautlet, Barri S.; Zheng, Xiaoping; Lombardo, Louis J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 13 p. 3766 - 3769

1007-16-53-溴-4-氟苯甲酸

639858-65-4N-环丙基-4-氟-3-(4-氧代丁基)苯甲酰胺

参考文献

Borzilleri, Robert M.; Bhide, Rajeev S.; Barrish, Joel C.; D'Arienzo, Celia J.; Derbin, George M.; Fargnoli, Joseph; Hunt, John T.; Jeyaseelan Sr., Robert; Kamath, Amrita; Kukral, Daniel W.; Marathe, Punit; Mortillo, Steve; Qian, Ligang; Tokarski, John S.; Wautlet, Barri S.; Zheng, Xiaoping; Lombardo, Louis J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 13 p. 3766 - 3769