3-羟基异恶唑-5-甲酸甲酯合成路线 （共 21 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in methanol T=0 - 10°C;
参考文献
Frey; Jager
Synthesis, 1985 , vol. NO. 12, p. 1100 - 1164
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane 2 h; Heating;
参考文献
Riess, Regine; Schoen, Michael; Laschat, Sabine; Jaeger, Volker
European Journal of Organic Chemistry, 1998 , # 3 p. 473 - 479
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane 2 h; Heating;
参考文献
Riess, Regine; Schoen, Michael; Laschat, Sabine; Jaeger, Volker
European Journal of Organic Chemistry, 1998 , # 3 p. 473 - 479
参考文献
Merck Sharp and Dohme Limited
Patent: US6200975 B1, 2001 ;
US 6200975 B1
反应条件
triethylamine in methanol 0.333333 h; Ambient temperature;
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 9-10 p. 478 - 480
反应条件
triethylamine in methanol
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 9-10 p. 478 - 480
反应条件
hydrogenchloride Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 20, p. 965 - 967
反应条件
sodium methylate in methanol 24 h; Ambient temperature; Yield given;
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 9-10 p. 478 - 480
反应条件
sodium methylate in methanol 24 h; Ambient temperature; Yield given;
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 9-10 p. 478 - 480
反应条件
sodium methylate in methanol 24 h; Ambient temperature; Yield given;
参考文献
Bulletin de la Societe Chimique de France, , vol. 2, # 9-10 p. 478 - 480
