2-((1S,2R)-2-羟基-1,2-二苯基乙基氨基)乙酸乙酯合成路线 （共 9 条）
反应条件
triethylamine in tetrahydrofuran T=20°C; 18 h;
参考文献
Chemical Communications, , vol. 49, # 80 p. 9131 - 9133
反应条件
2: Et3N / tetrahydrofuran / 25 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 108, # 5 p. 1103 - 1104
反应条件
1: 9.6 g / NaHCO3 / CH2Cl2; H2O / 12 h 2: 77.9 percent / p-toluenesulfonic acid monohydrate, CaCl2 / benzene / 8 h / Heating 3: 100 percent / N-bromosuccinimide / CCl4 / 0.75 h / Heating View Scheme
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
1: NaHCO3 / CH2Cl2; H2O 2: p-TsOH / benzene / Heating 3: NBS / CCl4 / 0.58 h / Heating 4: 1.) ZnCl2, 2.) H2 / 2.) PdCl2 / 1.) THF, 25 deg C, 2.) EtOH, 25 deg C, p= 20 psi View Scheme
参考文献
Sinclair, Peter J.; Zhai, Dongguan; Reibenspies, Joseph; Williams, Robert M.
Journal of the American Chemical Society, 1986 , vol. 108, # 5 p. 1103 - 1104
反应条件
1: aq. NaHCO3 / CH2Cl2 / 1 h / 0 °C 2: p-TsOH*H2O / toluene View Scheme
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
1: in toluene T=110°C; 13 h; 2: With toluene-4-sulfonic acid in toluene T=110°C; 1 h;
参考文献
Yeo, David J.; Warriner, Stuart L.; Wilson, Andrew J.
Chemical Communications, 2013 , vol. 49, # 80 p. 9131 - 9133
反应条件
1: toluene / 10 h / Heating 2: p-TsOH*H2O / toluene View Scheme
参考文献
Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557
反应条件
sodium hydrogencarbonate; sodium chloride in chloroform; water 20 h; Heating;
参考文献
Journal of the American Chemical Society, , vol. 110, # 5 p. 1547 - 1557
反应条件
1: NaHCO3, NaCl / CHCl3; H2O / 20 h / Heating 2: 73.4 percent / p-toluenesulfonic acid monohydrate, CaCl2 / benzene / 8 h / Heating 3: N-bromosuccinimide / CCl4 / 1 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 110, # 5 p. 1547 - 1557
