N,N-双(苄氧基羰基)胍合成路线 （共 5 条）
反应条件
sodium hydroxide in dichloromethane; water T=0°C;
参考文献
Igel, Patrick; Schneider, Erich; Schnell, David; Elz, Sigurd; Seifert, Roland; Buschauer, Armin
Journal of Medicinal Chemistry, 2009 , vol. 52, # 8 p. 2623 - 2627
反应条件
ammonia in methanol T=20°C; 3 h; Inert atmosphere;
参考文献
Limbach, Michael; Korotkov, Vadim S.; Es-Sayed, Mazen; De Meijere, Armin
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 20 p. 3816 - 3822
反应条件
sodium hydride in tetrahydrofuran T=0 - 20°C;
参考文献
Bristol-Myers Squibb Co.
Patent: US6335324 B1, 2002 ;
Location in patent: Page column 228 ;
US 6335324 B1
反应条件
sodium hydroxide in dichloromethane; water T=0°C; 20 h;
参考文献
Geyer, Roland; Igel, Patrick; Kaske, Melanie; Elz, Sigurd; Buschauer, Armin
MedChemComm, 2014 , vol. 5, # 1 p. 72 - 81
反应条件
sodium hydride Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 63, # 12 p. 3804 - 3805
