4-氯-1H-吡唑并[3,4-D]嘧啶-6-胺合成路线 （共 7 条）
参考文献
Synlett, , # 13 p. 1900 - 1904
反应条件
sodium isopropanolate 1 h; Heating;
参考文献
Seela, Frank; Becher, Georg
Synthesis, 1998 , # 2 p. 207 - 214
反应条件
1: 77 percent / i-PrONa / 1 h / Heating 2: 78 percent / NBS / 1,2-dichloro-ethane / 1.5 h / Heating View Scheme
参考文献
Seela, Frank; Becher, Georg
Synthesis, 1998 , # 2 p. 207 - 214
反应条件
sodium hydroxide 20 h; Heating;
参考文献
Taylor, Edward C.; Patel, Hemantkumar H.
Tetrahedron, 1992 , vol. 48, # 37 p. 8089 - 8100
反应条件
1: 90 percent / methanol / 1 h / Heating 2: 47 percent / KOH / tetrahydrofuran; H2O / 0.03 h / Ambient temperature 3: 69 percent / NaOMe / methanol / 2 h / Ambient temperature 4: 93 percent / NaOH / H2O / 24 h / Ambient temperature View Scheme
参考文献
Seela, Frank; Steker, Herbert
Heterocycles, 1985 , vol. 23, # 10 p. 2521 - 2524
反应条件
N-bromosuccinmide in 1,2-dichloro-ethane Heating / reflux;
参考文献
WO2007/134828 A1, ;
Page/Page column 70 ;
WO 2007/134828 A1
反应条件
sodium methylate; thiourea
1., MeOH, 1 h, reflux 2., MeOH, 15 min, reflux; Yield given. Multistep reaction;
参考文献
Seela; Steker
Helvetica Chimica Acta, 1986 , vol. 69, # 7 p. 1602 - 1613
