3-甲基-3H- 嘌呤-6(9H)-酮合成路线 （共 9 条）
反应条件
hydrogen; nickel in methanol T=25 - 40°C; P=760 Torr; 8 h;
参考文献
Heterocycles, , vol. 27, # 4 p. 885 - 888
反应条件
hydrogenchloride; sodium nitrite T=50 - 55°C; 3.5 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 6 p. 2213 - 2219
反应条件
1: 3 percent / 0.2N NaOH / 2 h / Ambient temperature 2: 66 percent / H2 / Raney Ni / methanol / 8 h / 25 - 40 °C / 760 Torr View Scheme
参考文献
Heterocycles, , vol. 27, # 4 p. 885 - 888
反应条件
1: 77 percent / 90percent H2SO4 / toluene / 1 h / 30 °C 2: 3 percent / 0.2N NaOH / 2 h / Ambient temperature 3: 66 percent / H2 / Raney Ni / methanol / 8 h / 25 - 40 °C / 760 Torr View Scheme
参考文献
Heterocycles, , vol. 27, # 4 p. 885 - 888
反应条件
1: 57 percent / 2N NaOH / 1 h / Ambient temperature 2: 77 percent / 90percent H2SO4 / toluene / 1 h / 30 °C 3: 3 percent / 0.2N NaOH / 2 h / Ambient temperature 4: 66 percent / H2 / Raney Ni / methanol / 8 h / 25 - 40 °C / 760 Torr View Scheme
参考文献
Heterocycles, , vol. 27, # 4 p. 885 - 888
反应条件
1: 38 percent / acetic anhydride / 1 h / Heating 2: 73 percent / sat. NH3 / methanol / 0 °C 3: 0.1 M HCl / H2O / 25 °C / pH 2.01 View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 6 p. 2213 - 2219
反应条件
sodium hydroxide 0.833333 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 36, # 1 p. 107 - 117
反应条件
hydrogenchloride T=40°C; 24 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 6 p. 2213 - 2219
反应条件
potassium carbonate in N,N-dimethyl acetamide 16 h; Ambient temperature;
参考文献
Fujii, Tozo; Saito, Tohru; Inoue, Isao; Kumazawa, Yukinari; Tamura, Katsumi
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 1 p. 107 - 117
