1-(咪唑-1-基)苯酚合成路线 （共 10 条）
反应条件
copper(l) iodide; potassium carbonate; L-proline; PS[DMVBIM][Pro] in dimethyl sulfoxide T=120°C; 60 h;
参考文献
Chen, Wen; Zhang, Yuanyuan; Zhu, Liangbo; Lan, Jingbo; Xie, Rugang; You, Jingsong
Journal of the American Chemical Society, 2007 , vol. 129, # 45 p. 13879 - 13886
反应条件
hydrogen bromide 12 h; Heating;
参考文献
Pratt, Derek A.; Pesavento, Russell P.; Van Der Donk, Wilfred A.
Organic Letters, 2005 , vol. 7, # 13 p. 2735 - 2738
反应条件
potassium phosphate; copper(l) iodide in N,N-dimethyl-formamide T=35 - 40°C; 40 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhu, Liangbo; Li, Gaocan; Luo, Liang; Guo, Peng; Lan, Jingbo; You, Jingsong
Journal of Organic Chemistry, 2009 , vol. 74, # 5 p. 2200 - 2202
反应条件
phosphoric acid T=210 - 220°C; 4 h;
参考文献
Tashiro, Masashi; Itoh, Takashi; Fukata, Gouki
Synthesis, 1982 , # 3 p. 217 - 219
反应条件
1.1: methanol; H2O / 20 °C 1.2: 82 percent / ammonium chloride; H3PO4 / methanol; H2O / Heating 2.1: 100 percent / aq. HBr / 12 h / Heating View Scheme
参考文献
Organic Letters, , vol. 7, # 13 p. 2735 - 2738
反应条件
1: 69 percent / CuBr, anhydrous K2CO3 / nitrobenzene / 30 h / 220 °C 2: 95 percent / 48percent HBr / 7 h / Heating View Scheme
参考文献
Farmaco, Edizione Scientifica, , vol. 42, # 3 p. 205 - 218
反应条件
NaH in N,N-dimethyl-formamide
参考文献
Nippon Soda Co., Ltd.
Patent: US5965743 A1, 1999 ;
反应条件
1: 130 °C 2: 6 N HCl 3: (CH3)3Al / CH2Cl2 4: CH3SO3H / H2O / pH 5-6 View Scheme
参考文献
Morgan Jr.; Lis; Lumma Jr.; Wohl; Nickisch; Phillips; Lind; Lampe; Di Meo; Reiser; Argentieri; Sullivan; Cantor
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1087 - 1090
反应条件
hydrogenchloride; potassium hydroxide; sodium hydroxide in methanol; ethanol; dichloromethane; water
参考文献
Schering A.G.
Patent: US4851526 A1, 1989 ;
参考文献
H. Lundbeck A/S
Patent: US2003/138376 A1, 2003 ;
