1-(4-甲醛基苯基)咪唑合成路线 （共 19 条）
反应条件
potassium carbonate; trans-1,2-diaminocyclohexane-based copper(II) complex in N,N-dimethyl-formamide T=110°C; 1.5 h;
参考文献
Kantam, M. Lakshmi; Ramani; Chakrapani
Synthetic Communications, 2008 , vol. 38, # 4 p. 626 - 636
反应条件
potassium carbonate; trans-1,2-diaminocyclohexane-based copper(II) complex in N,N-dimethyl-formamide T=110°C; 10 h;
参考文献
Kantam, M. Lakshmi; Ramani; Chakrapani
Synthetic Communications, 2008 , vol. 38, # 4 p. 626 - 636
反应条件
potassium carbonate; copper(l) iodide in N,N-dimethyl-formamide T=110°C; Ullmann coupling reaction; 24 h;
参考文献
Xi, Zhenxing; Liu, Fenghui; Zhou, Yongbo; Chen, Wanzhi
Tetrahedron, 2008 , vol. 64, # 19 p. 4254 - 4259
反应条件
potassium phosphate; copper(l) iodide in N,N-dimethyl-formamide T=35 - 40°C; 40 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhu, Liangbo; Li, Gaocan; Luo, Liang; Guo, Peng; Lan, Jingbo; You, Jingsong
Journal of Organic Chemistry, 2009 , vol. 74, # 5 p. 2200 - 2202
反应条件
hydrogenchloride 2 h; Ambient temperature;
参考文献
Cozzi, Paolo; Carganico, Germano; Fusar, Domenico; Grossoni, Mauro; Menichincheri, Maria; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 20 p. 2964 - 2972
反应条件
pyridinium chlorochromate in dichloromethane 1.5 h; Ambient temperature;
参考文献
Artico; Silvestri; Stefancich; Avigliano; Di Giulio; Maccarrone; Agostinelli; Mondovi; Morpurgo
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 3 p. 219 - 228
反应条件
in hydrogenchloride; N,N-dimethyl-formamide
反应条件
potassium carbonate in dimethyl sulfoxide T=20 - 164°C; 0.0833333 h; microwave irradiation;
参考文献
Meciarova, Maria; Podlesna, Janka; Toma, Stefan
Monatshefte fur Chemie, 2004 , vol. 135, # 4 p. 419 - 423
反应条件
potassium carbonate in dimethyl sulfoxide T=20 - 162°C; 0.0833333 h; microwave irradiation;
参考文献
Meciarova, Maria; Podlesna, Janka; Toma, Stefan
Monatshefte fur Chemie, 2004 , vol. 135, # 4 p. 419 - 423
反应条件
1: 51 percent / NaH / dimethylsulfoxide / 18 h / 100 °C 2: 57 percent / NaBH4, CaCl2 / tetrahydrofuran / Ambient temperature 3: 51 percent / pyridinium chlorochromate (PCC) / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 27, # 3 p. 219 - 228
