3-甲基-1,2-恶唑-5-羧酸甲酯合成路线 (共 6 条)
反应条件
triethylamine in diethyl ether T=18°C; 40 h;
参考文献
Journal of the Chemical Society. Perkin Transactions 2, , # 12 p. 2031 - 2038
反应条件
tert-butylhypochlorite 5 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 23 p. 1671 - 1672
反应条件
triethylamine in diethyl ether
参考文献
Chemische Berichte, , vol. 106, p. 3345 - 3367
反应条件
chlorine; potassium hydrogencarbonate 1.) 1.5M HCl, -10/-5 deg C; 2.) CH2Cl2, 75 min; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 50, # 22 p. 6643 - 6652
反应条件
diisobutylaluminium hydride in hexane T=-65°C; 2 h;
参考文献
Bell, David; Crowe, Eleanor A.; Dixon, Nicholas J.; Geen, Graham R.; Mann, Inderjit S.; Shipton, Mark R.
Tetrahedron, 1994 , vol. 50, # 22 p. 6643 - 6652
反应条件
ethanol; hydrazine hydrate
参考文献
Sacconi
Journal of the American Chemical Society, 1954 , vol. 76, p. 3400
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Meltzer et al.
Journal of the American Pharmaceutical Association (1912-1977), 1953 , vol. 42, p. 594,597