2-(2-氨基-6-氯苯基)-1-乙醇合成路线 （共 12 条）
反应条件
hydrogenchloride in ethanol; water; ethyl acetate
参考文献
Wakunaga Seiyaku Kabushiki Kaisha; Fujisawa Pharmaceutical Co., Ltd.
Patent: US5254685 A1, 1993 ;
反应条件
sodium sulfide; sulfur in ethanol; water 4 h; Heating;
参考文献
Florvall; Kumar; Ask; Fagervall; Renyi; Ross
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1406 - 1412
反应条件
1: DMSO, TritonB / methanol 2: H2 / 5percent Pd-C / ethyl acetate View Scheme
参考文献
Florvall; Kumar; Ask; Fagervall; Renyi; Ross
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1406 - 1412
反应条件
2: aq. H2SO4 3: H2SO4 4: (i) H2, Raney-Ni, (ii) LiAlH4 View Scheme
参考文献
Huisgen,R. et al.
Chemische Berichte, 1960 , vol. 93, p. 1496 - 1506
反应条件
1: aq. H2SO4 2: H2SO4 3: (i) H2, Raney-Ni, (ii) LiAlH4 View Scheme
参考文献
Huisgen,R. et al.
Chemische Berichte, 1960 , vol. 93, p. 1496 - 1506
反应条件
1: H2SO4 2: (i) H2, Raney-Ni, (ii) LiAlH4 View Scheme
参考文献
Huisgen,R. et al.
Chemische Berichte, 1960 , vol. 93, p. 1496 - 1506
反应条件
N-benzyl-trimethylammonium hydroxide; calcium chloride; zinc 1.) Me2SO, 95 deg C, 1 h, 2.) H2O, reflux; Multistep reaction;
参考文献
Tsuji, Yasushi; Huh, Keun-Tae; Yokoyama, Yasuharu; Watanabe, Yoshihisa
Journal of the Chemical Society, Chemical Communications, 1986 , # 21 p. 1575 - 1576
反应条件
(i) H2, Raney-Ni, (ii) LiAlH4; Multistep reaction;
参考文献
Huisgen,R. et al.
Chemische Berichte, 1960 , vol. 93, p. 1496 - 1506
反应条件
hydrogenchloride; thionyl chloride in diethyl ether; chloroform T=50°C; 2 h;
参考文献
Florvall; Kumar; Ask; Fagervall; Renyi; Ross
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1406 - 1412
反应条件
potassium carbonate; [pentamethylcyclopentadienylRhCl2]2 in acetone T=100°C; 20 h;
参考文献
Fujita, Ken-Ichi; Takahashi, Yoshinori; Owaki, Maki; Yamamoto, Kazunari; Yamaguchi, Ryohei
Organic Letters, 2004 , vol. 6, # 16 p. 2785 - 2788
