1: With boron tribromide in dichloromethane T=0 - 20°C; 2: With methanol in dichloromethane 3: With sodium hydrogencarbonate in water Saturated solution;
参考文献
AMBIT BIOSCIENCES CORPORATON
Patent: WO2009/117080 A1, 2009 ;
Location in patent: Page/Page column 171 ;
WO 2009/117080 A1