3-[2-[(E)-[3-(3-甲氧基-3-氧代-丙基)-4-甲基-5-[(E)-(3-甲基-5-氧代-4-乙烯基-吡咯-2-亚基)甲基]吡咯-2-亚基]甲基]-4-甲基-5-[(E)-(4-甲基-5-氧代-3-乙烯基-吡咯-2-亚基)甲基]-1H-吡咯-3-基]丙酸甲酯合成路线 （共 26 条）
反应条件
1: methanol; HBr 2: ueber mehrere Stufen View Scheme
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 274, p. 231,256
反应条件
sulfuric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone 1.) DMSO, 1 min, 20 deg C; 2.) 24 h, room temp.; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Monatshefte fuer Chemie, , vol. 120, p. 575 - 580
反应条件
sulfuric acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone 1.) DMSO, 1 min, 20 deg C; 2.) 24 h, room temp.; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Monatshefte fuer Chemie, , vol. 120, p. 575 - 580
反应条件
lithium borohydride in dimethyl sulfoxide Ambient temperature;
参考文献
Falk, Heinz; Marko, Helmut
Monatshefte fuer Chemie, 1991 , vol. 122, # 4 p. 319 - 321
反应条件
hydrogenchloride; sodium hydroxide; ethylenediaminetetraacetic acid; sodium cyanoborohydride 1.) CH3OH, 37 deg C, 30 min, 2.) CH3OH, ethanol, 5-10 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Sturrock; Bull; Kirsch
Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 3 p. 263 - 274
反应条件
sodium hydroxide in tetrahydrofuran; methanol; water 4 h; Ambient temperature;
参考文献
Hirota
Biological and Pharmaceutical Bulletin, 1995 , vol. 18, # 4 p. 481 - 484
