1-甲基-3,4-二氢-beta-咔啉-3-羧酸合成路线 （共 8 条）
反应条件
1: With dicyclohexyl-carbodiimide in dichloromethane T=20°C; 3 h; 2: With trifluoroacetic acid in dichloromethane T=50°C; 1 h;
参考文献
Brahmbhatt, Keyur G.; Ahmed, Nafees; Sabde, Sudeep; Mitra, Debashis; Singh, Inder Pal; Bhutani, Kamlesh K.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 15 p. 4416 - 4419
反应条件
hydrogenchloride; sodium nitrite in ethanol T=37°C; pH=3; 1 h;
参考文献
Diem, Stefanie; Gutsche, Birgit; Herderich, Markus
Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 12 p. 5993 - 5998
反应条件
trifluoroacetic acid in 1,2-dichloro-ethane T=50°C; 1 h;
参考文献
Letellier; Fleury; Torreilles; Previero
Journal of Heterocyclic Chemistry, 1988 , vol. 25, # 4 p. 1265 - 1270
反应条件
phosphate buffer T=37°C; Maillard reaction; pH=7.0; 672000 h;
参考文献
Masuda, Shuichi; Kanamori, Hisayuki; Kinae, Naohide
Bioscience, Biotechnology and Biochemistry, 2005 , vol. 69, # 11 p. 2232 - 2235
参考文献
Spenser
Canadian Journal of Chemistry, 1959 , vol. 37, p. 1851,1856
反应条件
1: POCl3 2: aq.-ethanolic NaOH View Scheme
参考文献
Spenser
Canadian Journal of Chemistry, 1959 , vol. 37, p. 1851,1856
反应条件
1: aqueous HCl 2: H2SO4 View Scheme
参考文献
Spenser
Canadian Journal of Chemistry, 1959 , vol. 37, p. 1851,1856
参考文献
Wrede; Feuerriegel
Chemische Berichte, 1933 , vol. 66, p. 1073,1074
