2-(羟甲基)-4-氨基吡啶合成路线 （共 4 条）
参考文献
MYREXIS, INC.; HOLCOMB, Ryan C.; SEBAHAR, Paul R.; SUZUKI, Kazuyuki; McLEOD, Donald A.; DASTRUP, David M.; HOARAU, Christophe; HALTER, Robert J.; BURSAVICH, Matthew Gregory; SHENDEROVICH, Mark D.; RICHARDS, Burt; BARTEL, Paul L.
Patent: WO2012/142329 A1, 2012 ;
Location in patent: Page/Page column 73-74 ;
WO 2012/142329 A1
反应条件
1: caesium carbonate / palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene / 1,4-dioxane / 4 h / Reflux 2: potassium hydroxide; ethanol / 2 h / Reflux View Scheme
参考文献
MYREXIS, INC.; HOLCOMB, Ryan C.; SEBAHAR, Paul R.; SUZUKI, Kazuyuki; McLEOD, Donald A.; DASTRUP, David M.; HOARAU, Christophe; HALTER, Robert J.; BURSAVICH, Matthew Gregory; SHENDEROVICH, Mark D.; RICHARDS, Burt; BARTEL, Paul L.
Patent: WO2012/142329 A1, 2012 ;
WO 2012/142329 A1
反应条件
iron in phosphate buffer T=22°C; pH=6.6; 0.333333 h; KineticsProduct distribution;
参考文献
Ghauch, Antoine
Chemosphere, 2001 , vol. 43, # 8 p. 1109 - 1117
反应条件
1: aq.-ethanolic KOH 2: aqueous KOH View Scheme
参考文献
Furukawa
Yakugaku Zasshi, 1959 , vol. 79, p. 487,491
Chem. Zentralbl., 1959 , vol. 130, p. 18028
