1: 84 percent / cupric acetate / dimethylformamide / 12 h / 90 °C 2: polyphosphate ester (PPE) / 1 h / 100 °C 3: 2 N ethanol. NaOH / 0.5 h / Heating 4: SOCl2 / 1 h / Heating 5: CH2Cl2 / 0.5 h / 20 °C 6: NH3(g) / various solvent(s) / 0.25 h / 110 - 120 °C View Scheme
参考文献
Rewcastle, Gordon W.; Atwell, Graham J.; Chambers, David; Baguley, Bruce C.; Denny, William A.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 4 p. 472 - 477
1: 84 percent / cupric acetate / dimethylformamide / 12 h / 90 °C 2: polyphosphate ester (PPE) / 1 h / 100 °C 3: 2 N ethanol. NaOH / 0.5 h / Heating 4: SOCl2 / 1 h / Heating 5: CH2Cl2 / 0.5 h / 20 °C 6: NH3(g) / various solvent(s) / 0.25 h / 110 - 120 °C View Scheme
参考文献
Rewcastle, Gordon W.; Atwell, Graham J.; Chambers, David; Baguley, Bruce C.; Denny, William A.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 4 p. 472 - 477
