1-(氯甲基)-4-硝基苯合成路线 （共 349 条）
反应条件
1: 81 percent / HNO3, H2SO4 / 1) 0 deg C, 30 min, 2) r.t., 1h
2: 68 percent / methanol / 0.25 h / 0 °C
3: 73 percent / m-chloroperbenzoic acid / CH2Cl2 / 20 h
View Scheme
参考文献
Berven; Dolphin; Withers
Canadian Journal of Chemistry, 1990 , vol. 68, # 10 p. 1859 - 1866
反应条件
ethanol; sodium hydrogencarbonate
参考文献
Iskander; Riad
Journal of the Chemical Society, 1951 , p. 2054,2057
参考文献
Lellmann; Pekrun
Justus Liebigs Annalen der Chemie, 1890 , vol. 259, p. 49
反应条件
1: alcohol; KOH; water / Trennung durch Behandeln mit Aceton
2: alcoholic ammonium sulfide / 100 °C / im geschlossenen Rohr
View Scheme
参考文献
Strakosch
Chemische Berichte, 1873 , vol. 6, p. 329
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; Alkylation; 8 h;
参考文献
Cho, Su-Dong; Kim, Hyeung-Jae; Ahn, Chuljin; Falckb; Shin, Dong-Soo
Tetrahedron Letters, 1999 , vol. 40, # 47 p. 8215 - 8217
反应条件
in N,N-dimethyl-formamide
1 h; Ambient temperature;
参考文献
Andrews, Adrian F.; Smith, David M.; Hodson, Harold F.; Thorogood, Peter B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 12 p. 2995 - 3006
参考文献
Wilcox, Craig S.
Tetrahedron Letters, 1985 , vol. 26, # 47 p. 5749 - 5752
反应条件
1.) 1 h, steam bath; 2.) 135-140 deg C, 48 h; Yield given;
参考文献
Spiessens, Luc I.; Anteunis, Marc J. O.
Bulletin des Societes Chimiques Belges, 1981 , vol. 90, # 11 p. 1167 - 1176
反应条件
ethanol; sodium ethanolate
参考文献
Bergel; Stock
Journal of the Chemical Society, 1954 , p. 2409,2414
Journal of the Chemical Society, 1959 , p. 90,93
参考文献
Burckhalter; Stephens
Journal of the American Chemical Society, 1951 , vol. 73, p. 56
